Health Benefits of Resveratrol
What is Resveratrol?
Resveratrol is a nutraceutical that has recently attracted a lot of research attention. In this blog, we will discuss and explain the main health benefits of resveratrol.
Resveratrol is found in many plants, peanuts, and berries. It is also present in red wine (concentration 0.1 – 14.3 mg/L).
It was first isolated in the 1940s when it was noticed that it had the ability to provide plants with resistance to microbial and fungal infection.
Resveratrol was found to be responsible for the “French Paradox”, the observation of an unexpectedly low rate of heart disease among Southern French people who consume a lot of red wine, despite their diet being high in saturated fat. 
What are the main health benefits of resveratrol?
In 2003, Dr. Sinclair, from Harvard University, discovered that resveratrol can extend the life span of animals anywhere from 24 percent to as much as 59 percent. He was sure that resveratrol can be just as effective for humans. 
Dr. Sinclair discovered, what no one else could, that resveratrol, when tested on a molecular level, was shown to turn on the SIRT1 gene. This is one of the main health benefits of resveratrol.
The SIRT1 gene that is the primary gene related to how quickly we age. It alters gene expression within the brain, heart, and skeletal muscle.
Mitochondria is a small organ in each cell that converts oxygen and food into energy. SIRT 1 can improve mitochondrial function and reduce inflammation.
It can, therefore, influence our health, weight loss, and longevity. This is another important health benefit of resveratrol. 
Scientists have long been trying to manipulate this gene, but up until the relatively recent discovery of resveratrol, the only way possible to achieve this was by initiating a semi-starvation condition within the body, known as (CR), or Caloric Restriction.
While this was very effective at manipulating the SIRT1 gene, it obviously was not practical nor particularly pleasant!
We actually can slow down or even reverse the aging process.
Resveratrol has been shown to mimic the effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects.
- Several animal studies and recent human clinical trials have focused on the ability of resveratrol to combat a variety of diseases such as type-2 diabetes, cardiovascular disorders, neurodegeneration, non-alcoholic fatty liver disease, and some types of cancer. 
- It also confers cardiometabolic health benefits, which include reducing inflammation autophagy, improving insulin sensitivity and glucose homeostasis and upregulating mitochondrial biogenesis. 
Clinical benefits of resveratrol summarized in :